Phenotyping Study of Cyclophosphamide 4-Hydroxylation in Malay Cancer Patients

BACKGROUND: Cyclophosphamide (CP) is an anticancer alkylating group (nitrogen mustard) and a prodrug that will be metabolized to form its active metabolite, 4-hydroxycyclophosphamide (4-OHCP). The various enzymes involved in its bioactivation can cause a wide range of CP expression and activity amon...

Descripción completa

Detalles Bibliográficos
Autores principales: Hasanah, Yesi Ihdina Fityatal, Harahap, Yahdiana, Purwanto, Denni Joko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849187/
https://www.ncbi.nlm.nih.gov/pubmed/33536743
http://dx.doi.org/10.2147/DDDT.S279128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849187/
https://www.ncbi.nlm.nih.gov/pubmed/33536743
http://dx.doi.org/10.2147/DDDT.S279128

Ejemplares similares