Lamin B1 decline underlies age‐related loss of adult hippocampal neurogenesis

Neurogenesis in the adult hippocampus declines with age, a process that has been implicated in cognitive and emotional impairments. However, the mechanisms underlying this decline have remained elusive. Here, we show that the age‐dependent downregulation of lamin B1, one of the nuclear lamins in adu...

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Detalles Bibliográficos
Autores principales: Bedrosian, Tracy A, Houtman, Judith, Eguiguren, Juan Sebastian, Ghassemzadeh, Saeed, Rund, Nicole, Novaresi, Nicole M, Hu, Lauren, Parylak, Sarah L., Denli, Ahmet M, Randolph‐Moore, Lynne, Namba, Takashi, Gage, Fred H, Toda, Tomohisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849303/
https://www.ncbi.nlm.nih.gov/pubmed/33300615
http://dx.doi.org/10.15252/embj.2020105819

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849303/
https://www.ncbi.nlm.nih.gov/pubmed/33300615
http://dx.doi.org/10.15252/embj.2020105819

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