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Lamin B1 decline underlies age‐related loss of adult hippocampal neurogenesis
Neurogenesis in the adult hippocampus declines with age, a process that has been implicated in cognitive and emotional impairments. However, the mechanisms underlying this decline have remained elusive. Here, we show that the age‐dependent downregulation of lamin B1, one of the nuclear lamins in adu...
Autores principales: | Bedrosian, Tracy A, Houtman, Judith, Eguiguren, Juan Sebastian, Ghassemzadeh, Saeed, Rund, Nicole, Novaresi, Nicole M, Hu, Lauren, Parylak, Sarah L., Denli, Ahmet M, Randolph‐Moore, Lynne, Namba, Takashi, Gage, Fred H, Toda, Tomohisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849303/ https://www.ncbi.nlm.nih.gov/pubmed/33300615 http://dx.doi.org/10.15252/embj.2020105819 |
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