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SATB2‐LEMD2 interaction links nuclear shape plasticity to regulation of cognition‐related genes

SATB2 is a schizophrenia risk gene and is genetically associated with human intelligence. How it affects cognition at molecular level is currently unknown. Here, we show that interactions between SATB2, a chromosomal scaffolding protein, and the inner nuclear membrane protein LEMD2 orchestrate the r...

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Detalles Bibliográficos
Autores principales: Feurle, Patrick, Abentung, Andreas, Cera, Isabella, Wahl, Nico, Ablinger, Cornelia, Bucher, Michael, Stefan, Eduard, Sprenger, Simon, Teis, David, Fischer, Andre, Laighneach, Aodán, Whitton, Laura, Morris, Derek W, Apostolova, Galina, Dechant, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849313/
https://www.ncbi.nlm.nih.gov/pubmed/33319920
http://dx.doi.org/10.15252/embj.2019103701