Tyrosine phosphorylation regulates hnRNPA2 granule protein partitioning and reduces neurodegeneration

mRNA transport in neurons requires formation of transport granules containing many protein components, and subsequent alterations in phosphorylation status can release transcripts for translation. Further, mutations in a structurally disordered domain of the transport granule protein hnRNPA2 increas...

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Detalles Bibliográficos
Autores principales: Ryan, Veronica H, Perdikari, Theodora M, Naik, Mandar T, Saueressig, Camillo F, Lins, Jeremy, Dignon, Gregory L, Mittal, Jeetain, Hart, Anne C, Fawzi, Nicolas L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849316/
https://www.ncbi.nlm.nih.gov/pubmed/33349959
http://dx.doi.org/10.15252/embj.2020105001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849316/
https://www.ncbi.nlm.nih.gov/pubmed/33349959
http://dx.doi.org/10.15252/embj.2020105001

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