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Learning from the worm: the effectiveness of protein-bound Moco to treat Moco deficiency

Molybdenum cofactor (Moco) is synthesized endogenously in humans and is essential for human development. Supplementation of Moco or its precursors has been explored as a therapy to treat Moco-deficient patients but with significant limitations. By using the nematode C. elegans as a model, Warnhoff a...

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Detalles Bibliográficos
Autores principales: Sewell, Aileen K., Han, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849358/
https://www.ncbi.nlm.nih.gov/pubmed/33526584
http://dx.doi.org/10.1101/gad.348176.120