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Substrate-dependent effects of quaternary structure on RNase E activity

RNase E is an essential, multifunctional ribonuclease encoded in E. coli by the rne gene. Structural analysis indicates that the ribonucleolytic activity of this enzyme is conferred by rne-encoded polypeptide chains that (1) dimerize to form a catalytic site at the protein-protein interface, and (2)...

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Detalles Bibliográficos
Autores principales: Moore, Christopher J., Go, Hayoung, Shin, Eunkyoung, Ha, Hye-Jeong, Song, Saemee, Ha, Nam-Chul, Kim, Yong-Hak, Cohen, Stanley N., Lee, Kangseok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849360/
https://www.ncbi.nlm.nih.gov/pubmed/33446571
http://dx.doi.org/10.1101/gad.335828.119