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SIX2 and SIX3 coordinately regulate functional maturity and fate of human pancreatic β cells
The physiological functions of many vital tissues and organs continue to mature after birth, but the genetic mechanisms governing this postnatal maturation remain an unsolved mystery. Human pancreatic β cells produce and secrete insulin in response to physiological cues like glucose, and these hallm...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849364/ https://www.ncbi.nlm.nih.gov/pubmed/33446570 http://dx.doi.org/10.1101/gad.342378.120 |