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SIX2 and SIX3 coordinately regulate functional maturity and fate of human pancreatic β cells

The physiological functions of many vital tissues and organs continue to mature after birth, but the genetic mechanisms governing this postnatal maturation remain an unsolved mystery. Human pancreatic β cells produce and secrete insulin in response to physiological cues like glucose, and these hallm...

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Detalles Bibliográficos
Autores principales: Bevacqua, Romina J., Lam, Jonathan Y., Peiris, Heshan, Whitener, Robert L., Kim, Seokho, Gu, Xueying, Friedlander, Mollie S.H., Kim, Seung K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849364/
https://www.ncbi.nlm.nih.gov/pubmed/33446570
http://dx.doi.org/10.1101/gad.342378.120