Esc2 orchestrates substrate-specific sumoylation by acting as a SUMO E2 cofactor in genome maintenance

SUMO modification regulates diverse cellular processes by targeting hundreds of proteins. However, the limited number of sumoylation enzymes raises the question of how such a large number of substrates are efficiently modified. Specifically, how genome maintenance factors are dynamically sumoylated...

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Detalles Bibliográficos
Autores principales: Li, Shibai, Bonner, Jacob N., Wan, Bingbing, So, Stephen, Mutchler, Ashley, Gonzalez, Leticia, Xue, Xiaoyu, Zhao, Xiaolan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849368/
https://www.ncbi.nlm.nih.gov/pubmed/33446573
http://dx.doi.org/10.1101/gad.344739.120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849368/
https://www.ncbi.nlm.nih.gov/pubmed/33446573
http://dx.doi.org/10.1101/gad.344739.120

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