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Robust Formation of an Epithelial Layer of Human Intestinal Organoids in a Polydimethylsiloxane-Based Gut-on-a-Chip Microdevice

Polydimethylsiloxane (PDMS) is a silicone polymer that has been predominantly used in a human organ-on-a-chip microphysiological system. The hydrophobic surface of a microfluidic channel made of PDMS often results in poor adhesion of the extracellular matrix (ECM) as well as cell attachment. The sur...

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Detalles Bibliográficos
Autores principales: Shin, Woojung, Ambrosini, Yoko M., Shin, Yong Cheol, Wu, Alexander, Min, Soyoun, Koh, Domin, Park, Sowon, Kim, Seung, Koh, Hong, Kim, Hyun Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849371/
https://www.ncbi.nlm.nih.gov/pubmed/33532747
http://dx.doi.org/10.3389/fmedt.2020.00002