Cis-acting variation is common across regulatory layers but is often buffered during embryonic development

Precise patterns of gene expression are driven by interactions between transcription factors, regulatory DNA sequences, and chromatin. How DNA mutations affecting any one of these regulatory “layers” are buffered or propagated to gene expression remains unclear. To address this, we quantified allele...

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Detalles Bibliográficos
Autores principales: Floc'hlay, Swann, Wong, Emily S., Zhao, Bingqing, Viales, Rebecca R., Thomas-Chollier, Morgane, Thieffry, Denis, Garfield, David A., Furlong, Eileen E.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849415/
https://www.ncbi.nlm.nih.gov/pubmed/33310749
http://dx.doi.org/10.1101/gr.266338.120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849415/
https://www.ncbi.nlm.nih.gov/pubmed/33310749
http://dx.doi.org/10.1101/gr.266338.120

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