TSA-seq reveals a largely conserved genome organization relative to nuclear speckles with small position changes tightly correlated with gene expression changes

TSA-seq mapping suggests that gene distance to nuclear speckles is more deterministic and predictive of gene expression levels than gene radial positioning. Gene expression correlates inversely with distance to nuclear speckles, with chromosome regions of unusually high expression located at the ape...

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Detalles Bibliográficos
Autores principales: Zhang, Liguo, Zhang, Yang, Chen, Yu, Gholamalamdari, Omid, Wang, Yuchuan, Ma, Jian, Belmont, Andrew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849416/
https://www.ncbi.nlm.nih.gov/pubmed/33355299
http://dx.doi.org/10.1101/gr.266239.120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849416/
https://www.ncbi.nlm.nih.gov/pubmed/33355299
http://dx.doi.org/10.1101/gr.266239.120

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