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Elimination of macrophages reduces glutaraldehyde‐fixed porcine heart valve degeneration in mice subdermal model

Glutaraldehyde‐fixed porcine heart valve (GPHV) calcify and deteriorate over time. The aim of this study was to explore the roles macrophages play in mediating calcification and degeneration of the valve's connective tissue matrix. GPHV were implanted subcutaneously in the abdomens of C57BL/6 m...

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Detalles Bibliográficos
Autores principales: Liu, Zongtao, Wang, Yixuan, Xie, Fei, Liu, Xing, Li, Fei, Dong, Nianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849454/
https://www.ncbi.nlm.nih.gov/pubmed/33523576
http://dx.doi.org/10.1002/prp2.716