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Genomic alterations in patients with somatic loss of the Y chromosome as the sole cytogenetic finding in bone marrow cells

Loss of the Y chromosome (LOY) is one of the most common somatic genomic alterations in hematopoietic cells in men. However, due to the high prevalence of LOY as the sole cytogenetic finding in the healthy older population, differentiating isolated LOY associated with clonal hematologic processes fr...

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Detalles Bibliográficos
Autores principales: Ouseph, Madhu M., Hasserjian, Robert P., Dal Cin, Paola, Lovitch, Scott B., Steensma, David P., Nardi, Valentina, Weinberg, Olga K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849577/
https://www.ncbi.nlm.nih.gov/pubmed/32193254
http://dx.doi.org/10.3324/haematol.2019.240689