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Biochemical, molecular and clinical aspects of coagulation factor VII and its role in hemostasis and thrombosis
Activated factor VII (FVIIa), the first protease of clotting, expresses its physiological procoagulant potential only after complexing with tissue factor (TF) exposed to blood. Deep knowledge of the FVIIa-TF complex and F7 gene helps to understand the Janus-faced clinical findings associated to low...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Fondazione Ferrata Storti
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849579/ https://www.ncbi.nlm.nih.gov/pubmed/33406812 http://dx.doi.org/10.3324/haematol.2020.248542 |