Targeting ganglioneuromas with mTOR inhibitors

We recently identified activated protein kinase B (PKB/AKT) as a tumorigenic driver in childhood ganglioneuroma. Inhibition of the mechanistic target of rapamycin (mTOR), a serine/threonine kinase downstream of AKT, effectively reduced the tumor burden in zebrafish with ganglioneuroma. We propose a...

Descripción completa

Detalles Bibliográficos
Autores principales: Tao, Ting, Shi, Hui, Durbin, Adam D., Look, A. Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Author’s Views
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849689/
https://www.ncbi.nlm.nih.gov/pubmed/33553609
http://dx.doi.org/10.1080/23723556.2020.1856621

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849689/
https://www.ncbi.nlm.nih.gov/pubmed/33553609
http://dx.doi.org/10.1080/23723556.2020.1856621

Ejemplares similares