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Bispecific antibody target pair discovery by high-throughput phenotypic screening using in vitro combinatorial Fab libraries
Bispecific antibodies can uniquely influence cellular responses, but selecting target combinations for optimal functional activity remains challenging. Here we describe a high-throughput, combinatorial, phenotypic screening approach using a new bispecific antibody target discovery format, allowing s...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849716/ https://www.ncbi.nlm.nih.gov/pubmed/33487120 http://dx.doi.org/10.1080/19420862.2020.1859049 |