Bispecific antibody target pair discovery by high-throughput phenotypic screening using in vitro combinatorial Fab libraries

Bispecific antibodies can uniquely influence cellular responses, but selecting target combinations for optimal functional activity remains challenging. Here we describe a high-throughput, combinatorial, phenotypic screening approach using a new bispecific antibody target discovery format, allowing s...

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Detalles Bibliográficos
Autores principales: Bhatta, Pallavi, Whale, Kevin D., Sawtell, Amy K., Thompson, Clare L., Rapecki, Stephen E., Cook, David A., Twomey, Breda M., Mennecozzi, Milena, Starkie, Laura E., Barry, Emily M. C., Peters, Shirley J., Kamal, Ahmad M., Finney, Helene M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849716/
https://www.ncbi.nlm.nih.gov/pubmed/33487120
http://dx.doi.org/10.1080/19420862.2020.1859049

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