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Common light chain chickens produce human antibodies of high affinity and broad epitope coverage for the engineering of bispecifics
Bispecific antibodies are an important and growing segment in antibody therapeutics, particularly in the immuno-oncology space. Manufacturing of a bispecific antibody with two different heavy chains is greatly simplified if the light chains can be the same for both arms of the antibody. Here, we int...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849766/ https://www.ncbi.nlm.nih.gov/pubmed/33491549 http://dx.doi.org/10.1080/19420862.2020.1862451 |