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Inhibited microRNA-494-5p promotes proliferation and suppresses senescence of nucleus pulposus cells in mice with intervertebral disc degeneration by elevating TIMP3

It has been unraveled that microRNAs (miRNAs) played crucial roles in processes of human diseases, while the role of miR-494-5p in intervertebral disc degeneration (IDD) remains scarcely studied. We aimed to investigate the mechanisms of miR-494-5p in IDD with the involvement of tissue inhibitor of...

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Detalles Bibliográficos
Autores principales: Chen, Gang, Zhou, Xiaopeng, Li, Hao, Xu, Zhengkuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849772/
https://www.ncbi.nlm.nih.gov/pubmed/33349112
http://dx.doi.org/10.1080/15384101.2020.1843812