Inhibition of aerobic glycolysis alleviates sepsis-induced acute kidney injury by promoting lactate/Sirtuin 3/AMPK-regulated autophagy

Metabolism reprogramming influences the severity of organ dysfunction, progression to fibrosis, and development of disease in acute kidney injury (AKI). Previously we showed that inhibition of aerobic glycolysis improved survival rates and protected septic mice from kidney injury. However, the under...

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Detalles Bibliográficos
Autores principales: Tan, Chuyi, Gu, Jia, Li, Tao, Chen, Huan, Liu, Ke, Liu, Meidong, Zhang, Huali, Xiao, Xianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849980/
https://www.ncbi.nlm.nih.gov/pubmed/33448325
http://dx.doi.org/10.3892/ijmm.2021.4852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7849980/
https://www.ncbi.nlm.nih.gov/pubmed/33448325
http://dx.doi.org/10.3892/ijmm.2021.4852

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