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The mutational landscape of spinal chordomas and their sensitive detection using circulating tumor DNA

BACKGROUND: Chordomas are the most common primary spinal column malignancy in the United States. The aim of this study was to determine whether chordomas may be detected by evaluating mutations in circulating tumor DNA (ctDNA). METHODS: Thirty-two patients with a biopsy-confirmed diagnosis of chordo...

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Detalles Bibliográficos
Autores principales: Mattox, Austin K, Yang, Beibei, Douville, Christopher, Lo, Sheng-fu, Sciubba, Daniel, Wolinsky, Jean Paul, Gokaslan, Ziya L, Robison, Jamie, Blair, Cherie, Jiao, Yuchen, Bettegowda, Chetan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7850091/
https://www.ncbi.nlm.nih.gov/pubmed/33543146
http://dx.doi.org/10.1093/noajnl/vdaa173