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An information-theoretic approach for measuring the distance of organ tissue samples using their transcriptomic signatures
MOTIVATION: Recapitulating aspects of human organ functions using in vitro (e.g. plates, transwells, etc.), in vivo (e.g. mouse, rat, etc.), or ex vivo (e.g. organ chips, 3D systems, etc.) organ models is of paramount importance for drug discovery and precision medicine. It will allow us to identify...
Autores principales: | Manatakis, Dimitris V, VanDevender, Aaron, Manolakos, Elias S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7850114/ https://www.ncbi.nlm.nih.gov/pubmed/32683449 http://dx.doi.org/10.1093/bioinformatics/btaa654 |
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