Cargando…

A novel nasal co-loaded loratadine and sulpiride nanoemulsion with improved downregulation of TNF-α, TGF-β and IL-1 in rabbit models of ovalbumin-induced allergic rhinitis

PURPOSE: The work aimed to develop a co-loaded loratadine and sulpiride nasal nanoemulsion for allergic rhinitis management. METHODS: Compatibility studies were conducted adopting differential scanning calorimetry and Fourier transform infrared spectroscopy. Nanoemulsion formulations were prepared u...

Descripción completa

Detalles Bibliográficos
Autores principales: Mohamad, Soad A., Safwat, Mohamed A., Elrehany, Mahmoud, Maher, Sherif A., Badawi, Ahmed M., Mansour, Heba F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7850330/
https://www.ncbi.nlm.nih.gov/pubmed/33501873
http://dx.doi.org/10.1080/10717544.2021.1872741