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Bioadhesive polymer/lipid hybrid nanoparticles as oral delivery system of raloxifene with enhancive intestinal retention and bioavailability

Raloxifene (RLX) is a second-generation selective estrogen receptor modulator used to treat osteoporosis in postmenopausal women. RLX fails to be developed into injectable dosage forms due to poor solubility. Although oral formulations are clinically available, the lower bioavailability (<2%) emb...

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Detalles Bibliográficos
Autores principales: Du, Xinhui, Gao, Na, Song, Xiaoyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7850345/
https://www.ncbi.nlm.nih.gov/pubmed/33501870
http://dx.doi.org/10.1080/10717544.2021.1872742