miR-34b-5p promotes renal cell inflammation and apoptosis by inhibiting aquaporin-2 in sepsis-induced acute kidney injury

OBJECTIVE: This study was designed to uncover the mechanism of miR-34b-5p-mediated aquaporin-2 (AQP2) in sepsis-induced injury using human renal tubular epithelial cells (HK-2). METHODS: Serum levels of miR-34b-5p, TNF-α, IL-1β, IL-6, serum creatinine (SCr), and blood urea nitrogen (BUN) in septic p...

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Detalles Bibliográficos
Autores principales: Zheng, Caifa, Wu, Dansen, Shi, Songjing, Wang, Liming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Laboratory Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7850462/
https://www.ncbi.nlm.nih.gov/pubmed/33494641
http://dx.doi.org/10.1080/0886022X.2021.1871922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7850462/
https://www.ncbi.nlm.nih.gov/pubmed/33494641
http://dx.doi.org/10.1080/0886022X.2021.1871922

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