A drug repurposing screen identifies hepatitis C antivirals as inhibitors of the SARS-CoV2 main protease

Effective SARS-CoV-2 antiviral drugs are desperately needed. The SARS-CoV-2 main protease (Mpro) appears as an attractive target for drug development. We show that the existing pharmacopeia contains many drugs with potential for therapeutic repurposing as selective and potent inhibitors of SARS-CoV-...

Descripción completa

Detalles Bibliográficos
Autores principales: Baker, Jeremy D., Uhrich, Rikki L., Kraemer, Gerald C., Love, Jason E., Kraemer, Brian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7850479/
https://www.ncbi.nlm.nih.gov/pubmed/33524017
http://dx.doi.org/10.1371/journal.pone.0245962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7850479/
https://www.ncbi.nlm.nih.gov/pubmed/33524017
http://dx.doi.org/10.1371/journal.pone.0245962

Ejemplares similares