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A lysine ring in HIV capsid pores coordinates IP6 to drive mature capsid assembly
The HIV capsid self-assembles a protective conical shell that simultaneously prevents host sensing whilst permitting the import of nucleotides to drive DNA synthesis. This is accomplished through the construction of dynamic, highly charged pores at the centre of each capsid multimer. The clustering...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7850482/ https://www.ncbi.nlm.nih.gov/pubmed/33524070 http://dx.doi.org/10.1371/journal.ppat.1009164 |