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Targeted next-generation sequencing-based detection of microsatellite instability in colorectal carcinomas

In the present study, we developed a computational method and panel markers to assess microsatellite instability (MSI) using a targeted next-generation sequencing (NGS) platform and compared the performance of our computational method, mSILICO, with that of mSINGS to detect MSI in CRCs. We evaluated...

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Detalles Bibliográficos
Autores principales: Lee, Yunbeom, Lee, Ji Ae, Park, Hye Eun, Han, Hyojun, Kim, Yuhnam, Bae, Jeong Mo, Kim, Jung Ho, Cho, Nam-Yun, Kim, Hwang-Phill, Kim, Tae-You, Kang, Gyeong Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7850495/
https://www.ncbi.nlm.nih.gov/pubmed/33524032
http://dx.doi.org/10.1371/journal.pone.0246356