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Activation of EphA2-EGFR signaling in oral epithelial cells by Candida albicans virulence factors

During oropharyngeal candidiasis (OPC), Candida albicans invades and damages oral epithelial cells, which respond by producing proinflammatory mediators that recruit phagocytes to foci of infection. The ephrin type-A receptor 2 (EphA2) detects β-glucan and plays a central role in stimulating epithel...

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Detalles Bibliográficos
Autores principales: Swidergall, Marc, Solis, Norma V., Millet, Nicolas, Huang, Manning Y., Lin, Jianfeng, Phan, Quynh T., Lazarus, Michael D., Wang, Zeping, Yeaman, Michael R., Mitchell, Aaron P., Filler, Scott G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7850503/
https://www.ncbi.nlm.nih.gov/pubmed/33471869
http://dx.doi.org/10.1371/journal.ppat.1009221