Osthole-Loaded Nanoemulsion Enhances Brain Target in the Treatment of Alzheimer's Disease via Intranasal Administration

Osthole (OST) is a natural coumarin compound that exerts multiple pharmacologic effects. However, the poor water solubility and the low oral absorption of OST limit its clinical application for the treatment of neurologic diseases. A suitable preparation needs to be tailored to evade these unfavoura...

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Detalles Bibliográficos
Autores principales: Song, Yilei, Wang, Xiangyu, Wang, Xingrong, Wang, Jianze, Hao, Qiulian, Hao, Jifu, Hou, Xueqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7850840/
https://www.ncbi.nlm.nih.gov/pubmed/33564364
http://dx.doi.org/10.1155/2021/8844455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7850840/
https://www.ncbi.nlm.nih.gov/pubmed/33564364
http://dx.doi.org/10.1155/2021/8844455

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