Cargando…
Osthole-Loaded Nanoemulsion Enhances Brain Target in the Treatment of Alzheimer's Disease via Intranasal Administration
Osthole (OST) is a natural coumarin compound that exerts multiple pharmacologic effects. However, the poor water solubility and the low oral absorption of OST limit its clinical application for the treatment of neurologic diseases. A suitable preparation needs to be tailored to evade these unfavoura...
Autores principales: | Song, Yilei, Wang, Xiangyu, Wang, Xingrong, Wang, Jianze, Hao, Qiulian, Hao, Jifu, Hou, Xueqin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7850840/ https://www.ncbi.nlm.nih.gov/pubmed/33564364 http://dx.doi.org/10.1155/2021/8844455 |
Ejemplares similares
-
Intranasal Administration of Dolutegravir-Loaded Nanoemulsion-Based In Situ Gel for Enhanced Bioavailability and Direct Brain Targeting
por: Nair, Anroop B., et al.
Publicado: (2023) -
In Vitro Evaluation of Curcumin- and Quercetin-Loaded Nanoemulsions for Intranasal Administration: Effect of Surface Charge and Viscosity
por: Vaz, Gustavo, et al.
Publicado: (2022) -
Curcumin and Quercetin-Loaded Lipid Nanocarriers: Development of Omega-3 Mucoadhesive Nanoemulsions for Intranasal Administration
por: Vaz, Gustavo Richter, et al.
Publicado: (2022) -
Neutrophils, as “Trojan horses”, participate in the delivery of therapeutical PLGA nanoparticles into a tumor based on the chemotactic effect
por: Hao, Jifu, et al.
Publicado: (2019) -
Osthole/borneol thermosensitive gel via intranasal administration enhances intracerebral bioavailability to improve cognitive impairment in APP/PS1 transgenic mice
por: Wu, Fanchang, et al.
Publicado: (2023)