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Highly Multiplexed Digital Spatial Profiling of the Tumor Microenvironment of Head and Neck Squamous Cell Carcinoma Patients

BACKGROUND: Immune checkpoint inhibitors (ICI) have shown durable and long-term benefits in a subset of head and neck squamous cell carcinoma (HNSCC) patients. To identify patient-responders from non-responders, biomarkers are needed which are predictive of outcome to ICI therapy. Cues in the tumor...

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Detalles Bibliográficos
Autores principales: Kulasinghe, Arutha, Taheri, Touraj, O’Byrne, Ken, Hughes, Brett G. M., Kenny, Liz, Punyadeera, Chamindie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851078/
https://www.ncbi.nlm.nih.gov/pubmed/33542903
http://dx.doi.org/10.3389/fonc.2020.607349