Cargando…

Highly Multiplexed Digital Spatial Profiling of the Tumor Microenvironment of Head and Neck Squamous Cell Carcinoma Patients

BACKGROUND: Immune checkpoint inhibitors (ICI) have shown durable and long-term benefits in a subset of head and neck squamous cell carcinoma (HNSCC) patients. To identify patient-responders from non-responders, biomarkers are needed which are predictive of outcome to ICI therapy. Cues in the tumor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kulasinghe, Arutha, Taheri, Touraj, O’Byrne, Ken, Hughes, Brett G. M., Kenny, Liz, Punyadeera, Chamindie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851078/ https://www.ncbi.nlm.nih.gov/pubmed/33542903 http://dx.doi.org/10.3389/fonc.2020.607349

Ejemplares similares

The prognostic significance of circulating tumor cells in head and neck and non‐small‐cell lung cancer
por: Kulasinghe, Arutha, et al.
Publicado: (2018)

Enrichment of circulating head and neck tumour cells using spiral microfluidic technology
por: Kulasinghe, Arutha, et al.
Publicado: (2017)

PD-L1 expressing circulating tumour cells in head and neck cancers
por: Kulasinghe, Arutha, et al.
Publicado: (2017)

A Collective Route to Head and Neck Cancer Metastasis
por: Kulasinghe, Arutha, et al.
Publicado: (2018)

Understanding the tumor microenvironment in head and neck squamous cell carcinoma
por: Rad, Habib Sadeghi, et al.
Publicado: (2022)

Impact of label-free technologies in head and neck cancer circulating tumour cells
por: Kulasinghe, Arutha, et al.
Publicado: (2016)

The Prognostic Role of Circulating Tumor Cells (CTCs) in Lung Cancer
por: Kapeleris, Joanna, et al.
Publicado: (2018)

A Pilot Study to Non-Invasively Track PIK3CA Mutation in Head and Neck Cancer
por: Schmidt, Henri, et al.
Publicado: (2018)

Short term ex-vivo expansion of circulating head and neck tumour cells
por: Kulasinghe, Arutha, et al.
Publicado: (2016)

Isolation of circulating tumor cells in non-small-cell-lung-cancer patients using a multi-flow microfluidic channel
por: Zhou, Jian, et al.
Publicado: (2019)

The Use of Three-Dimensional DNA Fluorescent In Situ Hybridization (3D DNA FISH) for the Detection of Anaplastic Lymphoma Kinase (ALK) in Non-Small Cell Lung Cancer (NSCLC) Circulating Tumor Cells
por: Kulasinghe, Arutha, et al.
Publicado: (2020)

Capture of Circulating Tumour Cell Clusters Using Straight Microfluidic Chips
por: Kulasinghe, Arutha, et al.
Publicado: (2019)

Clinical Applications of Circulating Tumour Cells and Circulating Tumour DNA in Non-Small Cell Lung Cancer—An Update
por: Kapeleris, Joanna, et al.
Publicado: (2022)

Phenotypic Characterization of Circulating Lung Cancer Cells for Clinically Actionable Targets
por: Kulasinghe, Arutha, et al.
Publicado: (2019)

The overexpression of salivary cytokeratins as potential diagnostic biomarkers in head and neck squamous cell carcinomas
por: Tang, Kai Dun, et al.
Publicado: (2017)

High-Plex and High-Throughput Digital Spatial Profiling of Non-Small-Cell Lung Cancer (NSCLC)
por: Monkman, James, et al.
Publicado: (2020)

Compartmentalized spatial profiling of the tumor microenvironment in head and neck squamous cell carcinoma identifies immune checkpoint molecules and tumor necrosis factor receptor superfamily members as biomarkers of response to immunotherapy
por: Sadeghirad, Habib, et al.
Publicado: (2023)

The Use of Microfluidic Technology for Cancer Applications and Liquid Biopsy
por: Kulasinghe, Arutha, et al.
Publicado: (2018)

An Occult HPV-Driven Oropharyngeal Squamous Cell Carcinoma Discovered Through a Saliva Test
por: Tang, Kai Dun, et al.
Publicado: (2020)

Ex vivo culture of circulating tumour cells derived from non-small cell lung cancer
por: Kapeleris, Joanna, et al.
Publicado: (2020)

Oral HPV16 DNA as a screening tool to detect early oropharyngeal squamous cell carcinoma
por: Tang, Kai D., et al.
Publicado: (2020)

Dissecting Tissue Compartment-Specific Protein Signatures in Primary and Metastatic Oropharyngeal Squamous Cell Carcinomas
por: Sadeghirad, Habib, et al.
Publicado: (2022)

Circulating biomarkers in patients with glioblastoma
por: Müller Bark, Juliana, et al.
Publicado: (2019)

DNA Methylation Changes in Human Papillomavirus-Driven Head and Neck Cancers
por: Ekanayake Weeramange, Chameera, et al.
Publicado: (2020)

Understanding the tumor microenvironment for effective immunotherapy
por: Sadeghi Rad, Habib, et al.
Publicado: (2020)

Salivary miRNA panel to detect HPV-positive and HPV-negative head and neck cancer patients
por: Wan, Yunxia, et al.
Publicado: (2017)

Spatial Profiling Identifies Prognostic Features of Response to Adjuvant Therapy in Triple Negative Breast Cancer (TNBC)
por: Kulasinghe, Arutha, et al.
Publicado: (2022)

Circulating tumour DNA alterations: emerging biomarker in head and neck squamous cell carcinoma
por: Huang, Xiaomin, et al.
Publicado: (2023)

Application of circulating tumour cells to predict response to treatment in head and neck cancer
por: Zhang, Xi, et al.
Publicado: (2022)

The evolving landscape of predictive biomarkers in immuno‐oncology with a focus on spatial technologies
por: Sadeghi Rad, Habib, et al.
Publicado: (2020)

Head and neck cancer N-glycome traits are cell line and HPV status–dependent
por: Rasheduzzaman, Mohammad, et al.
Publicado: (2022)

Current trends in the etiology and diagnosis of HPV-related head and neck cancers
por: Chai, Ryan C, et al.
Publicado: (2015)

Head and neck cancer patient-derived tumouroid cultures: opportunities and challenges
por: Basnayake, B. W. M. Thilini J., et al.
Publicado: (2023)

Isolation of Circulating Tumour Cells in Patients With Glioblastoma Using Spiral Microfluidic Technology – A Pilot Study
por: Müller Bark, Juliana, et al.
Publicado: (2021)

The Role of Circulating Biomarkers in Lung Cancer
por: Herath, Sayuri, et al.
Publicado: (2022)

The Performance of an Oral Microbiome Biomarker Panel in Predicting Oral Cavity and Oropharyngeal Cancers
por: Lim, Yenkai, et al.
Publicado: (2018)

A pilot study to compare the detection of HPV-16 biomarkers in salivary oral rinses with tumour p16(INK4a) expression in head and neck squamous cell carcinoma patients
por: Chai, Ryan C., et al.
Publicado: (2016)

Salivary DNA methylation panel to diagnose HPV-positive and HPV-negative head and neck cancers
por: Lim, Yenkai, et al.
Publicado: (2016)

Modelling reoxygenation effects in non-small cell lung cancer cell lines and showing epithelial-mesenchymal transition
por: Kapeleris, Joanna, et al.
Publicado: (2022)

Unlocking the Potential of Saliva-Based Test to Detect HPV-16-Driven Oropharyngeal Cancer
por: Tang, Kai Dun, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_0289suvvi40l46pjvf62gho56h