TDO2 Promotes the EMT of Hepatocellular Carcinoma Through Kyn-AhR Pathway

Tryptophan 2,3-dioxygenase (TDO2), an enzyme involved in tryptophan (Trp) metabolism has been linked with some malignant traits of various cancers. Kyn, the main product of Trp metabolism pathway catalyzed by TDO2 and indoleamine 2,3-dioxygenase (IDO) in tumor cells, was also demonstrated to activat...

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Detalles Bibliográficos
Autores principales: Li, Lei, Wang, Tao, Li, Shanbao, Chen, Zhengqian, Wu, Junyi, Cao, Wanyue, Wo, Qi, Qin, Xuebin, Xu, Junming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851084/
https://www.ncbi.nlm.nih.gov/pubmed/33542896
http://dx.doi.org/10.3389/fonc.2020.562823

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851084/
https://www.ncbi.nlm.nih.gov/pubmed/33542896
http://dx.doi.org/10.3389/fonc.2020.562823

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