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Haplotype Motif-Based Models for KIR-Genotype Informed Selection of Hematopoietic Cell Donors Fail to Predict Outcome of Patients With Myelodysplastic Syndromes or Secondary Acute Myeloid Leukemia

Results from registry studies suggest that harnessing Natural Killer (NK) cell reactivity mediated through Killer cell Immunoglobulin-like Receptors (KIR) could reduce the risk of relapse after allogeneic Hematopoietic Cell Transplantation (HCT). Several competing models have been developed to class...

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Detalles Bibliográficos
Autores principales: Schetelig, Johannes, Baldauf, Henning, Koster, Linda, Kuxhausen, Michelle, Heidenreich, Falk, de Wreede, Liesbeth C., Spellman, Stephen, van Gelder, Michel, Bruno, Benedetto, Onida, Francesco, Lange, Vinzenz, Massalski, Carolin, Potter, Victoria, Ljungman, Per, Schaap, Nicolaas, Hayden, Patrick, Lee, Stephanie J., Kröger, Nicolaus, Hsu, Kathy, Schmidt, Alexander H., Yakoub-Agha, Ibrahim, Robin, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851088/
https://www.ncbi.nlm.nih.gov/pubmed/33542712
http://dx.doi.org/10.3389/fimmu.2020.584520