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Label-free spectral imaging to study drug distribution and metabolism in single living cells
During drug development, evaluation of drug and its metabolite is an essential process to understand drug activity, stability, toxicity and distribution. Liquid chromatography (LC) coupled with mass spectrometry (MS) has become the standard analytical tool for screening and identifying drug metaboli...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851119/ https://www.ncbi.nlm.nih.gov/pubmed/33526869 http://dx.doi.org/10.1038/s41598-021-81817-0 |