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Label-free spectral imaging to study drug distribution and metabolism in single living cells

During drug development, evaluation of drug and its metabolite is an essential process to understand drug activity, stability, toxicity and distribution. Liquid chromatography (LC) coupled with mass spectrometry (MS) has become the standard analytical tool for screening and identifying drug metaboli...

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Detalles Bibliográficos
Autores principales: Alshammari, Qamar A., Pala, Rajasekharreddy, Katzir, Nir, Nauli, Surya M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851119/
https://www.ncbi.nlm.nih.gov/pubmed/33526869
http://dx.doi.org/10.1038/s41598-021-81817-0