Genetic aberrations in DNA repair pathways: a cornerstone of precision oncology in prostate cancer

Over the past years, several studies have demonstrated that defects in DNA damage response and repair (DDR) genes are present in a significant proportion of patients with prostate cancer. These alterations, particularly mutations in BRCA2, are known to be associated with an increased risk of develop...

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Detalles Bibliográficos
Autores principales: Lozano, Rebeca, Castro, Elena, Aragón, Isabel M., Cendón, Ylenia, Cattrini, Carlo, López-Casas, Pedro P., Olmos, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851123/
https://www.ncbi.nlm.nih.gov/pubmed/33106584
http://dx.doi.org/10.1038/s41416-020-01114-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851123/
https://www.ncbi.nlm.nih.gov/pubmed/33106584
http://dx.doi.org/10.1038/s41416-020-01114-x

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