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Three-dimensional low shear culture of Mycobacterium bovis BCG induces biofilm formation and antimicrobial drug tolerance

Mycobacteria naturally grow as corded biofilms in liquid media without detergent. Such detergent-free biofilm phenotypes may reflect the growth pattern of bacilli in tuberculous lung lesions. New strategies are required to treat tuberculosis, which is responsible for more deaths each year than any o...

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Detalles Bibliográficos
Autores principales: Cantillon, Daire, Wroblewska, Justyna, Cooper, Ian, Newport, Melanie J., Waddell, Simon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851154/
https://www.ncbi.nlm.nih.gov/pubmed/33526771
http://dx.doi.org/10.1038/s41522-021-00186-8