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Neonatal overfeeding during lactation rapidly and permanently misaligns the hepatic circadian rhythm and programmes adult NAFLD

Childhood obesity is a strong risk factor for adult obesity, type 2 diabetes, and cardiovascular disease. The mechanisms that link early adiposity with late-onset chronic diseases are poorly characterised. We developed a mouse model of early adiposity through litter size reduction. Mice reared in sm...

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Detalles Bibliográficos
Autores principales: Ribas-Aulinas, Francesc, Ribo, Silvia, Parra-Vargas, Marcela, Fernández-Pérez, Antonio, Cebrià, Judith, Guardiola-Perello, Maria, Ramon-Krauel, Marta, Lerin, Carles, Diaz, Ruben, Kalko, Susana G., Vallejo, Mario, Díez-Noguera, Antoni, Cambras, Trinitat, Jimenez-Chillaron, Josep C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851182/
https://www.ncbi.nlm.nih.gov/pubmed/33422644
http://dx.doi.org/10.1016/j.molmet.2021.101162