STRN-ALK rearranged pediatric malignant peritoneal mesothelioma – Functional testing of 527 cancer drugs in patient-derived cancer cells

Genetic rearrangements involving the anaplastic lymphoma kinase (ALK) gene create oncogenic drivers for several cancers, including malignant peritoneal mesothelioma (MPeM). Here, we report genomic and functional precision oncology profiling on a rare case of a 5-year old patient diagnosed with wide-...

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Detalles Bibliográficos
Autores principales: Murumägi, Astrid, Ungureanu, Daniela, Arjama, Mariliina, Bützow, Ralf, Lohi, Jouko, Sariola, Hannu, Kanerva, Jukka, Koskenvuo, Minna, Kallioniemi, Olli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851186/
https://www.ncbi.nlm.nih.gov/pubmed/33530027
http://dx.doi.org/10.1016/j.tranon.2021.101027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851186/
https://www.ncbi.nlm.nih.gov/pubmed/33530027
http://dx.doi.org/10.1016/j.tranon.2021.101027

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