Cargando…

Inhibitor of Differentiation 4 (ID4) represses mammary myoepithelial differentiation via inhibition of HEB

Inhibitor of differentiation (ID) proteins dimerize with basic HLH (bHLH) transcription factors, repressing transcription of lineage-specification genes across diverse cellular lineages. ID4 is a key regulator of mammary stem cells; however, the mechanism by which it achieves this is unclear. Here,...

Descripción completa

Detalles Bibliográficos
Autores principales: Holliday, Holly, Roden, Daniel, Junankar, Simon, Wu, Sunny Z., Baker, Laura A., Krisp, Christoph, Chan, Chia-Ling, McFarland, Andrea, Skhinas, Joanna N., Cox, Thomas R., Pal, Bhupinder, Huntington, Nicholas D., Ormandy, Christopher J., Carroll, Jason S., Visvader, Jane, Molloy, Mark P., Swarbrick, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851187/
https://www.ncbi.nlm.nih.gov/pubmed/33554073
http://dx.doi.org/10.1016/j.isci.2021.102072