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Inhibitor of Differentiation 4 (ID4) represses mammary myoepithelial differentiation via inhibition of HEB
Inhibitor of differentiation (ID) proteins dimerize with basic HLH (bHLH) transcription factors, repressing transcription of lineage-specification genes across diverse cellular lineages. ID4 is a key regulator of mammary stem cells; however, the mechanism by which it achieves this is unclear. Here,...
Autores principales: | Holliday, Holly, Roden, Daniel, Junankar, Simon, Wu, Sunny Z., Baker, Laura A., Krisp, Christoph, Chan, Chia-Ling, McFarland, Andrea, Skhinas, Joanna N., Cox, Thomas R., Pal, Bhupinder, Huntington, Nicholas D., Ormandy, Christopher J., Carroll, Jason S., Visvader, Jane, Molloy, Mark P., Swarbrick, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851187/ https://www.ncbi.nlm.nih.gov/pubmed/33554073 http://dx.doi.org/10.1016/j.isci.2021.102072 |
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