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Soluble Epoxide Hydrolase Hepatic Deficiency Ameliorates Alcohol-Associated Liver Disease

BACKGROUND & AIMS: Alcohol-associated liver disease (ALD) is a significant cause of liver-related morbidity and mortality worldwide and with limited therapies. Soluble epoxide hydrolase (sEH; Ephx2) is a largely cytosolic enzyme that is highly expressed in the liver and is implicated in hepatic...

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Detalles Bibliográficos
Autores principales: Mello, Aline, Hsu, Ming-Fo, Koike, Shinichiro, Chu, Bryan, Cheng, Jeff, Yang, Jun, Morisseau, Christophe, Torok, Natalie J., Hammock, Bruce D., Haj, Fawaz G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851189/
https://www.ncbi.nlm.nih.gov/pubmed/33068774
http://dx.doi.org/10.1016/j.jcmgh.2020.10.002