Mesenchymal stem cell-derived interleukin-28 drives the selection of apoptosis resistant bone metastatic prostate cancer

Bone metastatic prostate cancer (PCa) promotes mesenchymal stem cell (MSC) recruitment and their differentiation into osteoblasts. However, the effects of bone-marrow derived MSCs on PCa cells are less explored. Here, we report MSC-derived interleukin-28 (IL-28) triggers prostate cancer cell apoptos...

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Detalles Bibliográficos
Autores principales: McGuire, Jeremy J., Frieling, Jeremy S., Lo, Chen Hao, Li, Tao, Muhammad, Ayaz, Lawrence, Harshani R., Lawrence, Nicholas J., Cook, Leah M., Lynch, Conor C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851397/
https://www.ncbi.nlm.nih.gov/pubmed/33526787
http://dx.doi.org/10.1038/s41467-021-20962-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851397/
https://www.ncbi.nlm.nih.gov/pubmed/33526787
http://dx.doi.org/10.1038/s41467-021-20962-6

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