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Mesenchymal stem cell-derived interleukin-28 drives the selection of apoptosis resistant bone metastatic prostate cancer
Bone metastatic prostate cancer (PCa) promotes mesenchymal stem cell (MSC) recruitment and their differentiation into osteoblasts. However, the effects of bone-marrow derived MSCs on PCa cells are less explored. Here, we report MSC-derived interleukin-28 (IL-28) triggers prostate cancer cell apoptos...
Autores principales: | McGuire, Jeremy J., Frieling, Jeremy S., Lo, Chen Hao, Li, Tao, Muhammad, Ayaz, Lawrence, Harshani R., Lawrence, Nicholas J., Cook, Leah M., Lynch, Conor C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851397/ https://www.ncbi.nlm.nih.gov/pubmed/33526787 http://dx.doi.org/10.1038/s41467-021-20962-6 |
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