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CAFs-Derived Exosomal miRNA-130a Confers Cisplatin Resistance of NSCLC Cells Through PUM2-Dependent Packaging

PURPOSE: Chemoresistance is a significant barrier to the treatment and management of non-small cell lung cancer (NSCLC). Exosomes play an essential role in intercellular communication. Understanding the mechanism underlying the role of tumor stroma, especially cancer-associated fibroblasts (CAFs), d...

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Detalles Bibliográficos
Autores principales: Zhang, Tao, Zhang, Ping, Li, Hong-Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851405/
https://www.ncbi.nlm.nih.gov/pubmed/33542625
http://dx.doi.org/10.2147/IJN.S271976