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Single-cell RNA-seq dissects the intratumoral heterogeneity of triple-negative breast cancer based on gene regulatory networks

Triple-negative breast cancer (TNBC) is a subtype of breast cancer with high intratumoral heterogeneity. Recent studies revealed that TNBC patients might comprise cells with distinct molecular subtypes. In addition, gene regulatory networks (GRNs) constructed based on single-cell RNA sequencing (scR...

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Detalles Bibliográficos
Autores principales: Zhou, Shunheng, Huang, Yu-e, Liu, Haizhou, Zhou, Xu, Yuan, Mengqin, Hou, Fei, Wang, Lihong, Jiang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851423/
https://www.ncbi.nlm.nih.gov/pubmed/33575114
http://dx.doi.org/10.1016/j.omtn.2020.12.018