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Current understanding of cancer-intrinsic PD-L1: regulation of expression and its protumoral activity

In the last decade, we have witnessed an unprecedented clinical success in cancer immunotherapies targeting the programmed cell-death ligand 1 (PD-L1) and programmed cell-death 1 (PD-1) pathway. Besides the fact that PD-L1 plays a key role in immune regulation in tumor microenvironment, recently a p...

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Detalles Bibliográficos
Autores principales: Yadollahi, Pedram, Jeon, You-Kyoung, Ng, Wooi Loon, Choi, Inhak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851443/
https://www.ncbi.nlm.nih.gov/pubmed/33298250
http://dx.doi.org/10.5483/BMBRep.2021.54.1.241